U.S., May 24 -- ClinicalTrials.gov registry received information related to the study (NCT06988072) titled 'Study of Anti-BKPyV Immune Responses in Kidney Transplant Patients With BKPyV Viremia' on April 04.
Brief Summary: The human pathogen BK polyomavirus (BKPyV) is a ubiquitous, small, non-enveloped DNA virus that infects over 90% of people, typically in childhood with mild or no symptoms. Following primary infection, BKPyV establishes latency predominantly in the reno-urinary tract, and can occasionally be detected in the urine without any concomitant clinical symptoms. However, among kidney transplant recipients (KTR), due to impaired cellular and humoral immunity, uncontrolled viral replication in renal tubular epithelial cells (RPTE...