U.S., Jan. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07359092) titled 'Spexin and Phoenixin-20 in Girls With Central Precocious Puberty' on Jan. 14.
Brief Summary: Central precocious puberty (CPP) is characterized by the early activation of the hypothalamic-pituitary-gonadal axis in girls and may be difficult to distinguish from benign variants such as premature thelarche. Spexin and phoenixin-20 are novel neuropeptides that have been suggested to play roles in reproductive axis regulation.
The aim of this study was to compare serum spexin and phoenixin-20 levels among girls with central precocious puberty, girls with premature thelarche, and healthy age-matched controls. The study evaluated whether t...