U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07196605) titled 'Sodium Sivelestat With Mechanical Thrombectomy for Acute Stroke: A Pilot Study' on Sept. 21.
Brief Summary: Stroke remains a major global health burden, with acute ischemic stroke (AIS) accounting for more than 65% of all cases. Endovascular thrombectomy (EVT) has been established as the standard treatment for large vessel occlusion (LVO) stroke; however, the phenomenon of "futile recanalization" remains common, with nearly half of patients failing to achieve favorable outcomes despite successful vessel reperfusion. Increasing evidence indicates that neutrophils and neutrophil extracellular traps (NETs) play pivotal roles in post-r...