U.S., May 29 -- ClinicalTrials.gov registry received information related to the study (NCT06993142) titled 'Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage' on May 19.
Brief Summary: The goal of this clinical trial is two-fold. First to investigate the feasibility of whether a remotely administered smartphone app can increase the volume and intensity of physical activity in daily life in individuals with a LRRK2 G2019S or GBA1 N370S genetic mutation over a long period of time (24 months). Second, to explore the preliminary efficacy of exercise on markers for prodromal Parkinson's disease progression in individuals with a LRRK2 G2019S or GBA1 N370S genetic mutation.
Participants will be tasked to achieve an incremental increa...