U.S., Jan. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07341087) titled 'Skin Inflammation in Perimenopause: A Probiotic Intervention Proof of Concept Trial' on Dec. 11, 2025.
Brief Summary: This study will explore whether a daily probiotic drink containing Lactobacillus casei Shirota (LcS) can help improve immune function and reduce inflammation in women going through perimenopause. Hormonal changes during this stage of life can affect the immune system, gut health, and skin, sometimes leading to increased inflammation or conditions such as acne.
Participants will consume either a low-sugar LcS probiotic drink or a skimmed milk control drink every day for eight weeks. The study will assess markers of i...