U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT06878716) titled 'Silver Russell Syndrome, Parental Fertility and Assisted Reproductive Technology' on Feb. 21.
Brief Summary: Silver Russell Syndrome (SRS) is a rare imprinting disorder (about 1/16000). Parental imprinting is an epigenetic regulation phenomenon leading to the monoallelic expression of some genes. Its establishment takes place in the gametes and its maintenance is important at the early embryonic stage. Increase in the prevalence of conception by assisted reproductive technology (ART) has already been found in patients with imprinted disorder such as Angelman, Beckwith-Wiedemann or Prader Willi Syndromes, and more recently with SRS;...