U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT06919458) titled 'Short Course Steroids in Alcohol Associated Hepatitis' on April 02.
Brief Summary: Alcohol-associated hepatitis (AAH) is one of the most severe manifestations of the spectrum of alcohol related liver disease (ARLD), with high morbidity and mortality. Currently, corticosteroids are the standard of care for patients with severe AAH, but no consensus exists on the dosing schedule of steroids. We recently demonstrated that tapering prednisolone over 4 weeks reduces the risk of infections at day 90. However, we wanted to test whether the reduction in the duration of therapy would provide a similar benefit as tapering the dose of prednis...