Clinical Trial: Short and Long-term Responses of PD Symptoms to Earstim

U.S., Feb. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07400731) titled 'Short and Long-term Responses of PD Symptoms to Earstim' on Feb. 03.

Brief Summary: This is a prospective, multicenter, randomized, two-period study designed to evaluate the safety and effectiveness of the EarStim System for intermittent relief of motor symptoms in patients with Parkinson's disease experiencing wearing-off phenomena. Adult patients with moderate to severe Parkinson's disease (MDS-UPDRS Part III score >=33) receiving oral dopaminergic therapy will be enrolled. Period A is a randomized, double-blind, sham-controlled phase conducted in a clinical setting. Period B is an unblinded, standard-of-care-controlled phase eval...