U.S., March 4 -- ClinicalTrials.gov registry received information related to the study (NCT06854614) titled 'Sequential or CombinaTion Anti-obesitY Medication with Muscle Preservation for Weight Loss and MaintEnance: a PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)' on Feb. 21.
Brief Summary: This is a prospective, pragmatic, 21 month, single-center, randomized, 2-phased, open-label, parallel-group trial comparing the use of enhanced lifestyle changes (ELC) in two different sequential anti obesity medication (AOM) therapies. The ELC consists of a medically-supervised and comprehensive weight loss program (Cleveland Clinic's Department of Endocrinology, Diabetes and Metabolism's Integrated Weight Management Program). In the first p...