U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT06798571) titled 'Role of Menopause in Thermoregulation' on Jan. 15.

Brief Summary: The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group and age matched men.

Aging and reproductive hormones, specifically estrogen, independently alter responses to heat stress. However, the combined effects of low estrogen following menopause and aging on the response to heat stress are unknown. In this study, the investigators...