U.S., Jan. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07345325) titled 'Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve Endocarditis' on Dec. 12, 2025.

Brief Summary: The primary objective of this study is to demonstrate that a rifampin-free regimen is non-inferior to the rifampin-containing regimen in terms of all-cause mortality in staphylococcal prosthetic valve endocarditis within 6 months after randomization.

Study Start Date: Jan., 2026

Study Type: INTERVENTIONAL

Condition: Infective Endocarditis

Intervention: DRUG: Rifampin-free regimen

Rifampin-free regimen. The choice of other antibiotics is at the discretion of the physicians ...