U.S., Dec. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07300709) titled 'Renal Histopathology and Transcriptomic Analysis in Hepatorenal Syndrome During Liver Transplantation' on Oct. 02.
Brief Summary: Hepatorenal Syndrome (HRS) is a serious complication that can occur in patients with liver cirrhosis, characterised by kidney dysfunction, or acute kidney failure (AKI). While it has traditionally been thought that HRS affects structurally normal kidneys and is completely reversible with liver transplantation, recent evidence suggests this may not always be the case.
The purpose of this study is to examine the actual structural changes in the kidneys of patients with HRS through tissue biopsy and advance...