U.S., Sept. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07179874) titled 'Remote Ischemic Preconditioning to Prevent Contrast-Induced Kidney Injury in Diabetic Patients (PRINCES)' on Aug. 15.
Brief Summary: This study investigates whether remote ischemic preconditioning (RIPC)-a non-invasive technique involving brief cycles of blood flow restriction to the arm-can prevent contrast-induced nephropathy (CIN) in diabetic patients undergoing coronary angiography. Diabetes mellitus increases the risk of CIN due to heightened oxidative stress and disrupted protective cellular signaling.
While previous research suggests that RIPC may activate renal protective mechanisms, its efficacy in diabetic individuals re...