U.S., March 8 -- ClinicalTrials.gov registry received information related to the study (NCT06864312) titled 'Rebound Pain Following Regional Anaesthesia for Ankle Fracture Surgery' on March 03.
Brief Summary: Regional anaesthesia is a commonly used and effective analgesic modality in orthopaedic surgery. The benefits of peripheral nerve blocks (PNB) include better pain relief, limited opioid consumption and high patient satisfaction(1-3).
Following ankle fracture surgery, rebound pain has been reported. The rebound effect was demonstrated in a randomised control trial comparing pain after ankle fracture repair under general anaesthesia with or without PNB(4). An increase in pain scores was demonstrated after PNB resolution exceeding that ...