Clinical Trial: Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07108153) titled 'Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta' on July 18.

Brief Summary: The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of SION-719 when given to people with CF who are already taking Trikafta.

Study Start Date: Oct., 2025

Study Type: INTERVENTIONAL

Condition: Cystic Fibrosis (CF)

Intervention: DRUG: SION-719

All participants receive SION-719, as specified by their treatment sequence assignment

DRUG: Placebo-to-match SION-719

All participants receive placebo to match SION-719, a...