U.S., Nov. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07251777) titled 'Prone vs Supine Position in Potential Organ Donors: Multicenter Clinical Trial' on Jan. 26, 2024.
Brief Summary: Background and justification: In Argentina, 9,650 people are on the organ transplant waiting list, including 290 who require a lung transplant. In 2022, 21 unilateral lungs, 18 bilateral lungs, and one cardiopulmonary block were implanted, representing only 1.9% of all transplants. Maintaining organ viability in potential donors (PD) is challenging because brain death triggers adrenergic activation, hemodynamic instability, and atelectasis due to mechanical ventilation and loss of respiratory muscle activity. These factor...