U.S., Jan. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07341386) titled 'Prevention of Recurrence of Herpes Simplex in Autoimmune Rheumatic Diseases' on Jan. 05.
Brief Summary: The goal of this randomized, double-blind, placebo-controlled clinical trial is to evaluate the effectiveness and safety of oral suppressive therapy with acyclovir in preventing herpes simplex virus (HSV) reactivation in patients with autoimmune rheumatic diseases (ARDs) who have a history of recurrent HS episodes.
The main questions this study aims to answer are:
Does continuous oral acyclovir reduce the frequency of HSV reactivation in ARD patients compared to placebo? What is the safety profile of prolonged acyclovir use in t...