U.S., March 21 -- ClinicalTrials.gov registry received information related to the study (NCT06886464) titled 'Prevention of Nephrotoxin-Induced Acute Kidney Injury Using Cilastatin' on March 10.
Brief Summary: The goal of this clinical trial is to repurpose cilastatin for preventing acute kidney injury (AKI) in hospitalized patients receiving nephrotoxic medications. The trial will evaluate the efficacy of the re-purposed drug.
The main questions it aims to answer are:
- whether cilastatin will prevent nephrotoxic AKI in hospitalized patients.
Researchers will compare the drug cilastatin to a placebo (a look-alike substance that contains no drug) to see if drug cilastatin works to prevent AKI in hospitalized patients receiving nephrotox...