U.S., Feb. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07382362) titled 'Preventing Neurologic Complications in Valve Surgery' on Jan. 25.

Brief Summary: In patients with valvular heart disease and atrial fibrillation (AF) undergoing surgical valve surgery, current guidelines recommend concomitant surgical management of the left atrial appendage (LAA) to prevent postoperative thromboembolic events, particularly neurologic embolic events. However, whether concomitant LAA management benefits patients without AF by reducing postoperative neurologic complications remains controversial.

Given these uncertainties, this study aims to evaluate whether concomitant LAA suture closure during surgical valve surgery ...