U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT06837857) titled 'Prescription Opioids, Brain Structure, and Cognition in Older Adults with Chronic Pain' on Feb. 06.
Brief Summary: The purpose of this study is to determine whether exposure to prescription opioids is associated with brain structural changes on magnetic resonance imaging (MRI), with the primary outcome of white matter integrity as measured by fractional anisotropy of the corpus callosum.
Study Start Date: March 11
Study Type: INTERVENTIONAL
Condition:
Pain, Chronic
Intervention:
DRUG: Opioid
Subjects will receive oral oxycodone as needed for pain which will be titrated weekly based on pain response, adverse effects, and patie...