U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07000201) titled 'Preoperative Pregabalin vs Gabapentin in Elderly Undergoing Surgry,Controlled Trial' on May 23.
Brief Summary: Several studies have evaluated the efficacy of pregabalin in reducing preoperative anxiety, with inconsistent results. Similarly, inconclusive results have been reported regarding gabapentin and its effects in reducing preoperative anxiety. A previous study reported that a single dose of gabapentin or pregabalin administered 60 minutes before surgery in adults under general anesthesia was effective in reducing acute preoperative anxiety and elevated levels of sedation before and after surgery, with pregabalin having better a...