Clinical Trial: Population Pharmacokinetics of Remifentanil in Low-Weight Critically Ill Patients

U.S., Dec. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07301970) titled 'Population Pharmacokinetics of Remifentanil in Low-Weight Critically Ill Patients' on Nov. 29.

Brief Summary: The goal of this prospective clinical study is to learn about the population pharmacokinetics (PopPK), safety, and efficacy of remifentanil in low-body-weight patients in the Intensive Care Unit (ICU) who require mechanical ventilation. The main questions it aims to answer are:

1. What are the pharmacokinetic characteristics of remifentanil in low-weight ICU patients?

2. How does remifentanil (and concurrent propofol use) affect hemodynamic stability (such as blood pressure) and sedation efficacy in this population?

Parti...