U.S., Jan. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07364890) titled 'Platelet-Derived Growth Factors to Enhance Healing and Reduce Post-Extraction Complications in Smokers' on Dec. 13, 2025.
Brief Summary: This study is a randomized controlled clinical trial with a split-mouth design to evaluate the effect of Advanced Platelet-Rich Fibrin (A-PRF) application on socket healing following dental extractions in smokers. In the split-mouth design, each participant serves as their own control, minimizing inter-subject variability and controlling for potential confounders such as smoking habits, oral hygiene, and systemic health conditions.
Bilateral tooth extractions will be performed for each participant...