U.S., Jan. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07361263) titled 'Plasma Oxytocin Response to Oral Estrogens in Healthy Controls and AVP-Deficiency' on Jan. 05.

Brief Summary: The PHOENIX study aims to investigate whether oral estradiol valerate (EV) and ethinylestradiol (EE) can stimulate oxytocin (OXT) and neurophysin-1 (NP-1) release in humans. The goal is to assess their potential as a safe diagnostic stimulation test for oxytocin deficiency, particularly in patients with arginine vasopressin (AVP) deficiency.

Study Start Date: Jan. 09

Study Type: INTERVENTIONAL

Condition: AVP Deficiency Diabetes Insipidus

Intervention: DRUG: estradiol valerate

estradiol valerate

DRUG: esthinylestradio...