Clinical Trial: Pharmacokinetics and Safety of HRS-8427 in Healthy Volunteers and in Patients With Impaired Renal Function

U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07070375) titled 'Pharmacokinetics and Safety of HRS-8427 in Healthy Volunteers and in Patients With Impaired Renal Function' on July 08.

Brief Summary: This study evaluated the pharmacokinetic profile, safety, and tolerability of HRS-8427 injection in subjects with mild, moderate, severe, or end-stage renal disease (ESRD) requiring dialysis, using subjects with normal renal function as controls, to inform clinical dosing in patients with renal impairment.

Study Start Date: April 19, 2023

Study Type: INTERVENTIONAL

Condition: Gram-negative Bacterial Infections

Intervention: DRUG: HRS-8427

HRS-8427

Recruitment Status: COMPLETED

Sponsor: Jiang...