Clinical Trial: PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma.

U.S., July 9 -- ClinicalTrials.gov registry received information related to the study (NCT07053072) titled 'PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma.' on June 30.

Brief Summary: Evaluating the Safety and Efficacy of PD-1 mRNA LNP Vaccine Therapy in Patients with Primary Hepatocellular Carcinoma Who Have Failed Advanced Standard Therapy

Study Start Date: July 15

Study Type: INTERVENTIONAL

Condition: PD-1 mRNA LNP Vaccine Primary Liver Cancer

Intervention: DRUG: Low Dose PD-1 mRNA LNP Vaccine

Patients will receive PD-1 mRNA LNP vaccine at 50 mcg weekly for the first 4 doses and a 5th dose 1 month after the 4th dose.

DRUG: Medium dose PD-1 mRNA LNP vaccines

Patients will receive PD-1 mRNA LNP vaccine at 75 ...