U.S., Jan. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07320924) titled 'Patient-specific Reconstruction Plate for Segmental Mandibular Defects' on Dec. 20, 2025.
Brief Summary: The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require extensive intraoperative bending, often resulting in imperfect adaptation, press-to-contact fixation, and residual stresses that increase the risk of hardware fatigue and fracture. Recent advances in computer-aided design and manufacturing (CAD/CAM) and virtual surgical planning (VSP) have improved precision in...