U.S., July 26 -- ClinicalTrials.gov registry received information related to the study (NCT07085767) titled 'Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer' on July 08.

Brief Summary: This phase 3 clinical trial compares the efficacy and safety of palazestrant with ribociclib to letrozole and ribociclib in women and men who have not received prior systemic anti-cancer treatment for advanced breast cancer.

Study Start Date: Oct. 31, 2025

Study Type: INTERVENTIONAL

Condition: Breast Cancer Locally Advanced Breast Cancer Metastatic Breast Cancer ER Positive Breast Cancer HER2 Negative Breast Carcinoma

Intervention: DRUG: Palazestrant

Participants will be treated with palazes...