Clinical Trial: Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients

U.S., Dec. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07269223) titled 'Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients' on Nov. 25.

Brief Summary: This randomized controlled trial aims to evaluate the effect of oral vitamin D3 supplementation on inflammatory biomarkers and disease activity in Pakistani patients with moderate ulcerative colitis. Sixty patients will be randomized to receive either standard treatment alone/Placebo or standard treatment plus vitamin D3 (50,000 IU fortnightly) for 12 weeks. Primary outcomes include changes in blood (CRP, ESR, IL-6) and fecal (calprotectin) inflammatory biomarkers, and disease activity assessed by the partial Mayo score. Secon...