U.S., Oct. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07221617) titled 'Oral Methadone in Cardiac Surgery' on Oct. 25.

Brief Summary: The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.

Study Start Date: Jan. 01, 2026

Study Type: INTERVENTIONAL

Condition: Pain, Postoperative Anesthesia Cardiac Surgery

Intervention: DRUG: Methadone, oral

Patients will receive 0.4mg/kg PO methadone immediately prior to transport to the operating room

DRUG: Methadone, intravenously

Patients will receive 0.3mg/kg methadone intraveno...