Clinical Trial: ONE-HOUR POSITIVE PRESSURE VENTILATION AFTER A PRESSURE SUPPORT SPONTANEOUS BREATHING TRIAL: A RANDOMIZED CLINICAL TRIAL

U.S., Jan. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07324460) titled 'ONE-HOUR POSITIVE PRESSURE VENTILATION AFTER A PRESSURE SUPPORT SPONTANEOUS BREATHING TRIAL: A RANDOMIZED CLINICAL TRIAL' on Dec. 23, 2025.

Brief Summary: This is a randomized, open, multicenter, pragmatic, adaptive clinical trial with intention-to-treat analysis. The study will compare two weaning strategies from mechanical ventilation in critically ill patients admitted to intensive care units, with more than 72 hours of mechanical ventilation and with a successful spontaneous breathing trial on pressure support. Immediately after a successful spontaneous breathing trial, eligible patients will be randomized into 2 groups that will...