Clinical Trial: Oncolytic Virus in Esophageal Squamous Cell Carcinoma

U.S., July 12 -- ClinicalTrials.gov registry received information related to the study (NCT07061704) titled 'Oncolytic Virus in Esophageal Squamous Cell Carcinoma' on June 29.

Brief Summary: This clinical trial is designed to evaluate the preliminary efficacy and safety of an oncolytic virus combined with chemotherapy and an immune checkpoint inhibitor in patients with initially unresectable, locally advanced esophageal squamous cell carcinoma (ESCC). The primary endpoints are safety and event-free survival (EFS). Secondary endpoints include overall survival (OS), objective response rate (ORR), and quality of life (QoL). Exploratory endpoints include biomarker analyses such as single-cell sequencing.

Study Start Date: July 01

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