Clinical Trial: Natural History, Evolution, and Clinical Features of Autoimmune Atrophic Gastritis

U.S., Feb. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07388459) titled 'Natural History, Evolution, and Clinical Features of Autoimmune Atrophic Gastritis' on March 19, 2025.

Brief Summary: Autoimmune atrophic gastritis (AAG) is an immune-mediated disorder characterized by the loss of oxyntic glands and mucosal atrophy1.Specific autoantibodies directed to gastric parietal cells (PCA) and/or to intrinsic factors are inconstantly present1.Despite its morbidity, data on the epidemiology are scant. Its global prevalence has been estimated to be 0.5-4.5%.Hypo-achlorhydria and lack of intrinsic factor lead to malabsorption of many nutrients, as vit. B12, iron and calcium.A damage on elevated turnover cells may...