U.S., Aug. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07111351) titled 'Multi-omics Studies of Primary Aldosteronism' on Aug. 01.
Brief Summary: Primary aldosteronism is a prevalent yet underdiagnosed cause of secondary hypertension, contributing to significant cardiovascular morbidity and renal dysfunction. Despite affecting up to 20% of hypertensive patients, PA is frequently missed because it lacks distinctive clinical features and often presents with nonspecific symptoms like resistant hypertension or subtle electrolyte imbalances. The diagnostic pathway involves a stepwise approach: initial screening via the aldosterone-to-renin ratio, confirmatory testing (e.g., saline suppression or captopril chal...