Clinical Trial: Multi-Omics-Based Prediction of Allograft Dysfunction After Lung Transplantation

U.S., Nov. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07243964) titled 'Multi-Omics-Based Prediction of Allograft Dysfunction After Lung Transplantation' on Nov. 17.

Brief Summary: By establishing a prospective, multicenter lung transplantation clinical cohort, this study aims to systematically evaluate the utility of cfDNA fragmentomics, peripheral blood single-cell sequencing, and proteomics in monitoring and predicting graft dysfunction after lung transplantation, and to develop a multi-omics predictive model for early identification, dynamic monitoring, and mechanistic investigation of acute lung allograft dysfunction (ALAD) and chronic lung allograft dysfunction (CLAD).

Study Start Date: Nov. 01 ...