U.S., Dec. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07294599) titled 'Morning Versus Evening Patching in Childhood Amblyopia' on Dec. 08.
Brief Summary: To determine whether the time of day at which daily occlusion (patching) is administered - morning (08:00-10:00) versus evening (17:00-19:00) - affects the amount of visual-acuity improvement in the amblyopic eye in children with unilateral amblyopia.
Rationale:
While occlusion therapy remains the mainstay for treatment of childhood amblyopia, existing trials have focused on patching duration, not on the timing of occlusion. Diurnal or chronobiological factors - such as fluctuations in neuroplasticity, attention, compliance, or visual demand during ...