U.S., June 7 -- ClinicalTrials.gov registry received information related to the study (NCT07009392) titled 'Microbiological Molecular Profile of the Knee Joint During Primary Reconstruction or Revision Surgery of the ACL' on May 29.

Brief Summary: Anterior cruciate ligament (ACL) reconstructions are common surgical procedures, but a significant number fail for reasons that are not fully understood.

Silent infections have been shown to cause failure after other orthopedic surgical procedures such as fracture fixation and joint replacement. Silent and subclinical infections, as well as disruptions in the knee joint microbiome, could therefore be potential causes of failure after ligament reconstruction.

Traditional infection diagnostic met...