U.S., Nov. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07226076) titled 'Methadone in TKA for Post-op Pain and Opioid Reduction' on Nov. 06.
Brief Summary: This randomized, double-blind controlled trial investigates whether intraoperative IV methadone (0.15 mg/kg based on ideal body weight) reduces acute postoperative pain and opioid consumption in patients undergoing elective total knee arthroplasty under spinal anesthesia with mepivacaine.
Study Start Date: Nov. 28
Study Type: INTERVENTIONAL
Condition:
Post Operative Pain
Intervention:
DRUG: Methadone Hydrochloride
Patients will intraoperatively be administered methadone 0.15mg/kg IV, based on ideal body weight.
Recruitment Status: NOT_YET_RECR...