U.S., April 24 -- ClinicalTrials.gov registry received information related to the study (NCT06940570) titled 'Methadone as an Alternative Treatment for Children Underdoing HSCT' on March 17.
Brief Summary: Mucositis is a normal side effect of stem cell transplant which happens as a result of chemotherapy being given prior to a new donor cell infusion (bone marrow transplant). The chemotherapy will kill cancer cells, but good cells, such as those in the mouth, are killed too. The mouth cells going away causes the areas in the mouth to be blistered, irritated, sore, and extremely painful. Pain medication (usually morphine or hydromorphone if allergic to morphine) are given when oral blisters are seen or felt by patient in patient's mouth. Ho...