Clinical Trial: Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

U.S., Dec. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07291297) titled 'Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma' on Dec. 17.

Brief Summary: The purpose of this research study is to see how metformin, when used in combination with standard of care (SOC) treatment for metastatic (cancer that has spread) soft tissue sarcoma can improve patient outcomes.

Study Start Date: Feb., 2026

Study Type: INTERVENTIONAL

Condition: Sarcoma Metastatic Sarcoma, Soft Tissue

Intervention: DRUG: Metformin Hydrochloride ER

Participants will initially take 1000mg ER of metformin by mouth daily for 14 da...