U.S., July 31 -- ClinicalTrials.gov registry received information related to the study (NCT07092683) titled 'Mediation Analysis in Cardiac Surgery' on July 20.
Brief Summary: This study investigates the mediating role of intraoperative allogeneic red blood cell transfusion in the relationship between preoperative anaemia and postoperative complications in patients undergoing cardiac surgery. Using mediation analysis methods, we aim to determine whether and to what extent intraoperative transfusion explains the association between preoperative anaemia and adverse postoperative outcomes. By elucidating this pathway, the study seeks to inform perioperative blood management strategies and support more personalized, risk-adapted approaches to m...