Clinical Trial: Lung Response to a Higher PEEP During Severe Pneumonia: a CT Study

U.S., Aug. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07112976) titled 'Lung Response to a Higher PEEP During Severe Pneumonia: a CT Study' on July 03.

Brief Summary: At their institution, the investigators routinely assess the individual response of mechanically ventilated patients with acute respiratory failure to higher positive end-expiratory pressure (PEEP) by examining changes in lung aeration through lung computed tomography (CT). They typically obtain two lung CT scans during an end-expiratory hold, one at a PEEP of 10 cmH2O and another at 15 cmH2O. Recruitment and hyperinflation are measured by assessing the decrease in the volume of non-aerated lung regions (with a density greater than -100 HU)...