Clinical Trial: Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome)

U.S., July 24 -- ClinicalTrials.gov registry received information related to the study (NCT07081464) titled 'Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome)' on July 07.

Brief Summary: This study investigates whether cognitive dysfunction in young patients with congenital central hypoventilation syndrome (Ondine Syndrome) is related to the severity of the disease and dysfunction of the locus coeruleus (a brainstem structure involved in autonomic control and cognition). The investigators will assess cognitive evoked potentials (P300 wave) using high-resolution EEG during attention tasks, pupillometry, brain MRI, neuropsychological tests, and heart rate variability. Patients with different severities of PHOX2B gene mut...