Clinical Trial: LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.

U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07376135) titled 'LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.' on Dec. 14, 2025.

Brief Summary: The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of Alzheimer's disease or related dementias but do not yet have significant cognitive impairment.

The main question the study aims to answer are:

* Whether the structured hybrid multidomain lifestyle intervention is feasible (e.g., adherence and retention rate), and...