U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07000162) titled 'LAttice Radiation Therapy for Large Lesions: Reggio Emilia Single-arm Phase II Trial' on May 23.
Brief Summary: This study evaluates the activity and toxicity of Lattice Radiation Therapy (LRT) in patients with large, unresectable non-brain neoplastic lesions requiring palliative treatment. Eligible patients will 5 fractions LRT, delivered in every other day, to 20 Gy with a simultaneous boost to a minimum median dose of 50 Gy. No concomitant antineoplastic drugs will be allowed. Patients will be followed at 14, 30, 60, and 90 days after treatment, then every 3 months up to 1 year. Tumor response will be assessed using objective resp...