U.S., April 25 -- ClinicalTrials.gov registry received information related to the study (NCT06943859) titled 'Ketamine for Opioid Use Disorder' on April 09.

Brief Summary: The goal of this clinical trial is to learn if ketamine works to reduce craving for opioids in adults entering methadone treatment for opioid use disorder. The main questions it aims to answer are:

* Does ketamine reduce craving for opioids in patients with opioid use disorder?

* Does ketamine reduce symptoms of opioid withdrawal such as depression, pain, and poor sleep quality?

* Do patients who take ketamine stay in methadone treatment longer, and/or have better treatment outcomes than those given the placebo?

Researchers will compare ketamine to an active placebo ...