Clinical Trial: JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program with or Without Semaglutide in Adolescents with Obesity - a Randomized Controlled Trial

U.S., March 1 -- ClinicalTrials.gov registry received information related to the study (NCT06852391) titled 'JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program with or Without Semaglutide in Adolescents with Obesity - a Randomized Controlled Trial' on Jan. 06.

Brief Summary: The Joule MARS study is a single center, randomized, open label clinical trial aiming to explore the metabolic adaptations that occur in response to weight management in adolescents with obesity. Behavioural lifestyle intervention with and without a pharmacological intervention - semaglutide- will be studied. Study participants will be randomized to one of two groups. Group A will follow a behavioral lifestyle program (BLP) alone...