U.S., Nov. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07252544) titled 'Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)' on Sept. 09.
Brief Summary: The goal of this multicenter, double-blind, 2x2 factorial randomized controlled trial is to evaluate the efficacy and safety of isosorbide mononitrate, butylphthalide, and their combination in reducing disability in patients with acute lacunar stroke.
Study Start Date: Dec. 01
Study Type: INTERVENTIONAL
Condition:
Stroke, Lacunar
Stroke, Acute Ischemic
Cerebral Small Vessel Diseases
Intervention:
DRUG: Isosorbide Mononitrate
Days 1-7: Isosorbide mononitrate injection, 20 mg onc...