U.S., Jan. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07312149) titled 'Isolation of Pulmonary Veins Using the Box Technique in Patients Undergoing Sternotomy' on Dec. 16, 2025.
Brief Summary: Atrial Fibrillation (AF) is the most common cardiac arrhythmia worldwide, affecting approximately 2.8% of the population, with prevalence increasing with age. AF is associated with significant morbidity and mortality, accounting for about 25% of ischemic strokes, 10% of cryptogenic strokes, and a 10-40% annual increase in hospital admissions due to heart failure or anticoagulant-related events.
About 10% of patients undergoing cardiac surgery have preoperative AF. In 1986, Dr. Cox introduced the MAZE procedure, a ...