U.S., Feb. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07394257) titled 'Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis' on Jan. 19.
Brief Summary: Bacterial keratitis is a potentially sight-threatening corneal infection that is commonly treated with intensive topical antibiotics. Despite appropriate therapy, some cases show inadequate clinical response, particularly when the infection involves the deep corneal stroma. Limited penetration of topical antibiotics into deeper corneal layers may contribute to treatment failure in these recalcitrant cases.
Intrastromal antibiotic injection is a targeted drug-delivery approach that allows high local antimicrobial concent...